Directly measure force and rate of contraction
TARA’s Cardiotype assays have been validated with a large panel of inotropes. We can measure the important parameters of contraction including force and kinetics in a dose-dependent manner.
Evaluate healthy and patient-derived cardiac biology
Cardiotype tissues can be generated from both healthy subjects and patients. We can utilize iPSC-derived cardiomyocytes from commercial sources as well as your proprietary cell lines.
Applications for drug development
We can support all aspects of the drug discovery process, including target validation, compound optimization, biomarker identification & validation, and preclinical safety assessment.
Supporting Information
Take a deeper look at Cardiotype and cardiac drug discovery at TARA.
Whitepaper: Cardiac Drug Discovery Reignited
TARA pioneers new tools to unlock genetically defined diseases
Cardiotype Drug Discovery Data Modules
Learn how TARA is transforming the drug discovery paradigm for heart disease
Cardiotype
Cardiotype is TARA’s mature cardiac tissue engineered from induced-pluripotent stem cells (iPSCs). It reproduces the physiological hallmarks of the human heart and provides an integrated analysis of cardiac function, with both healthy and diseased models. Learn if your novel compound is safe.
